Please contact us for complete waters refurbishedused mass spectrometer system, warranty and service contract details. Hi everybody, where could i find a stepbystep user manual. Considerations specific to the xevo g2 qtof solventleakage hazard the source exhaust system is designed to be robust and leaktight. Waters xevo g2s qtof is a high resolution, high sensitivity instrument. Low ms sensitivity on qtof mass spectrometers wkb91752. The xevo g2xs qtof is for research use only and is not intended for use in diagnostic applications. Ionbench with the agilent qtof 6545 mass spectrometer. Jun 29, 2016 2017 waters corporation 62company confidential in summary our lcms workflows for oligonucleotide analysis. Collision cell, and quantof technology for superior robustness, sensitivity, and selectivity along. Unlike any other exact mass msms benchtop system on the market, xevo qtof mass spectrometer from waters corp. A monosaccharide, peptide chain or a substituent such as hso 3, etn can be added or deleted and branching points and anomeric linkages can be modified at the click of a button. While it maintains the integrated workflow benefits of engineered simplicity found in our existing xevo qtof, it also incorporates the groundbreaking quantof technology of our synapt g2 system.
Concerning the convenience of the xevo g2s qtof, i can say that the use of masslynx and targetlynx software provided by waters for targeted analysis was relatively practical and can afford a. This manual is a companion to the masslynx nt users guide supplied with the instrument. Q3, qtof or orbitrap lcms which will be better for. Can anyone help with an orbitrap mass spectrometer. See the xevo qtof ms in action and learn how you can gain. View online or download waters xevo g2 qtof operators, overview and maintenance manual. I am leaning towards waters xevo g2xs qtof with uplc acquity hclass with pda or shimadzu qtof lcms9030. The xevo tqs and xevo g2 qtof are the newest members of the xevo family of benchtop mass spectrometers first introduced in 2008 and are the most powerful mass spectrometers in their class. Overview to scale the picture below is a simulation at scale of the waters xevo g2xs qtof lcms mass spectrometer system right side connected with an acquity uhplc left side, installed on a ionbench ms mass spec bench or table.
Warnings are given throughout this manual where care is required to avoid personal injury. When you develop methods, follow the protocol for the adoption of analytical. Both the electrospray desolvation heater and the apci probe heater use this connector. Delivery and installation of msworkstation bench for agilent 6470. Its improved chromamatographic resolution is paired with a stateoftheart mass spectrometer such as the xevo g2s qtof or synapt g2si hdms systems. Watch this xevo g2 qtof animation to learn how you can obtain the highest quality, most comprehensive information that will enable you to. Waters acquity hclass uplc with pda and column manager.
Waters xevo g2xs qtof manuals manuals and user guides for waters xevo g2xs qtof. Glycan and glycopeptide analysis tmt quantitation mass. The varian hs602 qty 1 vacuum pump is enclosed in the msquietbox ii noise reduction system, under the waters xevo g2xs qtof lcms mass spectrometer. The probe and source components can be contaminated warning. Mobile laboratory bench for waters xevo g2xs qtof lcms. Overview and maintenance manual waters xevo g2xs qtof overview and maintenance manual.
Waters xevo g2 qtof community, manuals and specifications. Download waters xevo g2 qtof operators, overview and. A core element of the system is the hdx manager, which is purposebuilt to manage samples separated under higher operating pressures, at 0 c and with no compromise in deuterium recovery. The roughing pump was switched into the manual on position. The following products are compatible with the esi probe capillary and perlast oring. On the tune page, go to the setup dropdown menu and. Waters designed the orthogonal acceleration, timeofflight xevo g2s qtof. How to calibrate ms over an extended high mass range using sodium iodide nai or similar salts in masslynx for synapt g2 and xevo g2 and later wkb18128. Operators, overview and maintenance manual waters xevo g2 qtof operators, overview and maintenance manual 249 pages. Restart software and select pump down from the vacuum menu. Qtof 2 users guide micromass uk limited floats road. At present we have a wide variety of instruments using ei, ci, fd. Prepare prior to testing samples, intellistart technology automatically performs mass calibration, system checks, and monitors system performance to assure scientists.
Overview to scale the picture below is a simulation at scale of the agilent qtof 6545 system spectrometer connected with an agilent 1290 infinity ii lc, installed on a ionbench ms mass spec bench or table. This means that the data acquired for metabolite identification, impuritydegradant, peptideproteinantibody studies is of the highest reliability. Waters xevo g2xs quadrupole timeofflight qtof ms university of alabama mass spectrometry facility quadrupole theory oatof 4 hyperbolic or cylindrical rods with the combination of dc u and rf voltages v applied on the rods motion of ion in quadrupole fields. We are experiencing some noise problems with our new qtof mass spectrometer waters xevo g2xs. It is suitable for identifying and quantifying compounds in a complex matrix over a large dynamic range. The end result is classleading quantitative performance in real everyday laboratory conditions, demonstrated by limits of detection and. This is designed for use with both gas and liquid sample inlet device, specifically a dedicated uplc and api gc.
The waters xevo g2xs qtof stateoftheart accurate mass system, provides the highest quality hrms data, with mass accuracies in the sub 1 mda range. Xevo g2 qtof is a nextgeneration benchtop exact mass msms mass spectrometer and is the first xevo timeofflight mass spectrometer to feature waters quantoftm technology, currently only available with waters synapttm g2 ms and g2 hdms mass spectrometers. Minimum requirements are a reversed phase chromatography with either a linear. John gebler at waters and members of the utah faculty. It is equipped with a waters uplc for lcmsms analysis with an esi source. In addition, designated campus research core facilities crcfs have demonstrated excellence is facility operation and professional management.
Waters expands xevo ms instrument platform with next. Analytical facility research college of pharmacy uthsc. Whats more, the design philosophy uses innovative engineering to reduce complexity, improve easeofuse and tell you more about your samples. Waters introduces xevo g2xs qtof and xevo tqs micro mass. Xevo qtof resource page college of engineering umass amherst. Contact scanco today scanco analytical instruments.
This technology brings researchgrade quantitative and qualitative analytical performance to. Let xevo qtof ms bring intelligent engineering and new levels of simplicity and productivity to every step of your analytical workflow. This technology brings researchgrade quantitative and qualitative analytical. On the manual optimization page, click to stop the liquid flow.
Waters corporation expands xevo ms instrument platform. At uc davis a wide variety of equipment and services is available to all researchers on and off campus through shared resource facilities srfs. Low desolvation gas flow on xevo tqs wkb116288 waters. This instrument is of high sensitivity, high resolution, and accurate mass on low volatility samples, especially organics and biomolecules. Ionbench with the waters xevo g2xs qtof mass spectrometer. In detail, the instrument is connected to a waters. Xevo g2 qtof is the most sensitive, exact mass, quantitative and qualitative benchtop msms system.
Overview and maintenance manual waters xevo g2xs qtof overview and maintenance manual 306 pages. Srfs and crcfs provide access to technologies, training, and high quality scientific, technical services. Waters xevo g2 qtof operators, overview and maintenance manual. Walkup for trained advanced users guided assisted usage for frequent users facility personnel run. Hi everybody, where could i find a stepbystep user manual for. The aim of the facility is to provide mass, msms and hrms analysis for determining the elemental composition of the probable structures of various samples and also, to train our students on mass spectrometry. Contact scanco for instrument sales, technical support or general inquiries costa rica, panama, nicaragua, republica dominicana, guatemala, ecuador. Waters xevo tqd xevo tqd from waters is designed for quantitative uplcmsms applications, so you can confidently quantify and confirm trace components in the most complex of samples. Waters xevo g2xs qtof quadrupole timeofflight mass. Waters xevo tqxs, xevo tqs micro, xevo tqs, and acquity tqd, one thermo qexactive lcmsms, two waters xevo g2xs qtof lcmsms systems, and a shimadzu cfrplus malditof mass spectrometer. Flip the switch on the roughing pump into the manual off position. Failing manual calibration on a xevo g2xs qtof wkb11634.
The xevo g2xs qtof mass spectrometer combines the new xs collision cell with the proven, signature technologies of tofmrm, stepwave tm and quantof tm to deliver optimum levels of robust sensitivity and selectivity, resulting in the detection of more lowlevel compounds than ever before. Shop new and used waters quattro premier xes for sale on labx. Reference fluidics system error in the console for a xevo g2. Available options for krss mobile laboratory benches. During long analyses, critical hardware components stay clean for longer, so results are more reproducible and the laboratory stays productive.
On the instrument console system tree, click xevo g2 qtof manual optimization. The xevo g2xs qtof combines stepwave ion optics, xs. How to shut down or vent a qtof or synapt for a planned shutdown wkb1047. Waters corporation expands xevo ms instrument platform with. Our recommended laboratory bench for an waters xevo g2xs qtof lcms instrument connected to an waters lc is the krss msws08r workstation. Waters recommends you perform a hazard analysis, assuming a maximum leak into the laboratory atmosphere of 10% lc eluate. For detailed test instructions, please refer to the protocol described in the.
View online or download waters xevo g2xs qtof overview and maintenance manual. We have 1 waters xevo g2 qtof manual available for free pdf download. Agilent 6520 university of washington school of pharmacy. Thermo persuades me to q exactive focus orbitrap lcms. The xevo g2xs qtof combines stepwave ion optics, xs collision cell, and quantof technology for superior robustness, sensitivity, and selectivity along with dynamic range, mass accuracy, and speed of analysis, resulting in the highest quality, most comp rehensive qualitative and quantitative information. Measurements of magnetic moments of bulk and thin film samples. Intended use of the xevo g2xs qtof waters designed the orthogonal acceleration, timeofflight xevo g2xs qtof for use as a research tool to deliver authenticated mass measurement. Lct premierxe, qtof api us and ultima family, quattro lc, micro api, premierxe, ultima, ultimapt, sq detector and detector 2, tq detector, synapt g2 hdms,g2s, hdms, xevo g2 qtof tof, g2s qtof tof, qtof ms, tqms, tqs, tqd, zq. How to reboot a xevo series quadrupole ms masslynx wkb1075. Some small molecules i run in lcms waters xevo esi qtof tend to fragment. Refurbished waters xevo g2 qtof pn 186005597 complete with esi source, pump and masslynx pc workstation. If the instrument is used in a manner not specified by the manufacturer, the protection provided by the equipment may be impaired. Considerations specific to the xevo g2s qtof solventleakage hazard the source exhaust system is designed to be robust and leaktight.
Purchase and get quotes on lab equipment, supplies, and instrumentation. We have 1 waters xevo g2xs qtof manual available for free pdf download. High resolution mass spectrometry lab indian institute. The new waters xevo g2s qtof instrument from waters corporation the symposium was a very engaging and well attended event organized by chemistry alumnus dr.
Unlike some mobile workbench laboratory bench manufacturers, our innovative design allows us to install the msworkstation within your laboratory rather than just delivering to your goods in. Nitrogen gas generator for lcms galak chromatography. Laboratory equipment waters xevo g2xs qtof overview and maintenance manual 306 pages. Waters xevo g2xs qtof mass spectrometer coupled with 1 acuity uplc mclass with hdx technology and 2 acuity uplc iclass system. The xevo g2xs qtof combines stepwave ion optics with the xs collision cell, providing a significant increase in sensitivity with no reduction in selectivity. We are also a core facility of the delaware biotechnology institute. Xevo g2 qtof operators overview and maintenance guide waters. Hi everybody, where could i find a stepbystep user. Xevo qtof resource page university of massachusetts amherst.
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