Familiarity with narcolepsy is low and screening instruments are required. Epworth, ullanlinna narcolepsy scale, and stanford cataplexy questionnaires. Clinical, polysomnographic and laboratory characteristics of. Cerebrospinal fluid csf hypocretin1 deficiency is associated with definite clear cut cataplexy in patients with narcolepsy.
Spanning the latest advances in the field, this source covers current diagnostic procedures, genetic developments, explorations of animal models, new definitions and criteria, and improved. The uns was an 11item scale that investigated the subjects two main aspects of narcolepsy. The diagnoses of the participants were narcolepsy type 1 nt1, n 89, narcolepsy type 2. Those n 75 having a uns score equal or higher than the lowest value in a narcolepsy patient group were studied. Ullanlinna narcolepsy scale includes items about sleep latency how fast do you usually fall asleep in the evening.
Sep 27, 2005 the ullanlinna narcolepsy scale score was 30 of 44 a score of 14 suggests narcolepsy, and the swiss narcolepsy scale score was. Ullanlinna narcolepsy scale in diagnosis of narcolepsy sleep. The ullanlinna narcolepsy scale uns is a simple questionnairebased method used to measure the symptoms of the narcoleptic syndrome. Specifically, the scale was shifted to refine ratings on a perweek basis and limit.
The swiss narcolepsy score sns is based on five questions, a score ullanlinna narcolepsy scale score of 21. Ullanlinna narcolepsy scale in diagnosis of narcolepsy. Cureus attentiondeficithyperactivity disorder patients. If you suspect you have narcolepsy, discuss your concerns with a medical professional familiar with narcolepsy and other sleep disorders. We show that ullanlinna narcolepsy scale has excellent sensitivity and specificity in the screening of narcolepsy type 1 in a clinical population. Entry criteria included a ullanlinna narcolepsy scale uns score of 1044 and the identification of a partner or friend to participate in the research. The epworth sleepiness scale ess, the ullanlinna narcolepsy scale uns, and more recently the swiss narcolepsy scale. The aims of the present study are 1 to assess the value of the sns in a new series of patients with narcolepsy with cataplexy nc, and 2 to compare its sensitivity and. Ullanlinna narcolepsy scale uns was applied to all subjects and those with a uns score ofor 14 were contacted by phone for semistructured interview. Swiss narcolepsy scale narcolepsy with cataplexy test. Sleep restriction therapy, stimulus control therapy, ullanlinna narcolepsy scale, narcolepsy tips, sleep diary, stanford.
The 11item ullanlinna narcolepsy scale uns is a widely used. You can print out each complete page, illustrations, graphs, tables, references and abstracts, pages as slides, lists of available audiovisual programs, and forms for patients and physicians. Swiss narcolepsy scale meaning, range, results, scoring. See the finding a doctor section of this website for more information on finding a sleep specialist. The relationship between csf hypocretin1 levels and other narcoleptic symptoms including excessive daytime sleepiness, eds is not properly understood. Epworth sleepiness scale daytime sleepiness horneostberg chronotype, circadian typology f1 ullanlinna narcolepsy scale narcolepsy f1 berlin questionnaire sleep apnea restless leg syndrome screening questionnaire restless legs syndrome f1 munich questionnaire parasomnia f1. The impact of narcolepsy and its treatment a european study. Parkinsons disease and narcolepsy symptoms practiceupdate. The uns is an 11item questionnaire that assesses eds and cataplexy, with 7. Epworth sleepiness scale, sleep hygiene tips, sleep restriction therapy, stimulus control therapy, ullanlinna narcolepsy scale, narcolepsy. To validate ullanlinna narcolepsy scale uns as a screening tool for narcolepsy in a clinical population and to compare it with. A cutoff of 14 has been shown to have a high sensitivity 10096% but a variable specificity 9956% for patients with narcolepsy cataplexy 31,33.
Hlatyping, electrophysiological studies conventional polysomnography, mslt, 1week actigraphy, and measurements of csf levels of hypocretin and leptin were also performed. Sleep center ullanlinna narcolepsy scale 0 1 2 3 4 0 1 2 3 4. Jul 11, 2007 narcolepsy is caused by a dysregulation of areas in the midbrain and brainstem, with a loss of orexin a neuropeptide function as a typical finding. The 11item ullanlinna narcolepsy scale uns is a widely used screening instrument for narcolepsy 34. We recruited 226 patients mean age 48 years, 65% female who underwent inperson interviews and completed.
Ullanlinna narcolepsy scale is another questionnaire that can help determine the possibility of narcolepsy with cataplexy, which is the most common type. Diagnostic aids such as a modified epworth scale and the ullanlinna scale are discussed. The finnish study suggested that the scale was very sensitive 100% and specific 98. Scores higher than 14 at the epworth sleepiness scale or at the ullanlinna narcolepsy scale are typical for narcolepsy. Tomi sarkanen central finland central hospital academia. The epworth sleepiness scale ess, the ullanlinna narcolepsy scale uns, and more recently the swiss narcolepsy scale sns were used as screening tools for narcolepsy. Summary the ullanlinna narcolepsy scale uns is a simple questionnaire. To validate ullanlinna narcolepsy scale uns as a screening tool for narcolepsy in a clinical population and to. The ullanlinna narcolepsy scale named after the clinic in finland where it was developed is also a wellvalidated questionnaire for diagnosing narcolepsy with cataplexy.
There are various sorts of scales that are being utilized to screen the narcolepsy which are the epworth sleepiness scale ess, the ullanlinna narcolepsy scale uns, and all the more as of late the swiss narcolepsy scale sns. These free educational resources are provided to help you learn more about narcolepsy and its symptoms, and to help you discuss your symptoms with a sleep specialist. The swiss narcolepsy scale sns is a brief questionnaire designed to screen for a symptom profile that might be suggestive of narcolepsy. Awareness of narcolepsy is low and screening tools needed. Print out the ullanlinna narcolepsy scale pdf to assess your symptoms. Although the narcolepsyspecific scales currently in use may identify type 1 narcolepsy, there. We used data from the bern sleepwake database to investigate the discriminating capacity of both the sns and the epworth sleepiness scale ess to identify narcolepsy type 1 and type 2 in patients with central disorders of hypersomnolence cdh or sleepy. The uns is a simple 11item questionnairebased scale range 044 addressing the two main features of narcolepsy. The ullanlinna narcolepsy scale uns is an 11item questionnaire used to measure the symptoms of narcolepsy in adults and children.
Narcolepsy hypersomnias, journal of sleep research 10. Secondary narcolepsy caused by tumors in the hypothalamic region has been described in a few cases. Please circle the number that best describes each situation. Do you sleep during the day take naps no need i wanted but cannot sleep twice weekly or less on 35 days weekly daily or almost daily. Epworth sleepiness scale ess, ullanlinna narcolepsy scale uns, and sip. The swiss narcolepsy score sns is based on five questions, a score narcolepsy scale sns for the diagnosis of narcolepsy type 1. High baseline uns ullanlinna narcolepsy scale, indicating severe sleepiness but not ivig treatment, was associated with a reduction in narcolepsy symptoms. The occurrence of suspected narcolepsy ullanlinna narcolepsy scale. Clinical assessment included bmi, epworth sleepiness scale ess, ullanlinna narcolepsy scale uns, and history of remsymptoms sleep paralysis, hallucinations. The uns is an 11item scale designed to evaluate a variety of symptoms relating to narcolepsy, including frequency of daytime narcoleptic episodes, muscle weakness associated with powerful emotions, and nighttime sleep latency.
However, its important to note that some narcoleptic peoplethose with whats called type 2 narcolepsy dont experience that symptom. In multivariateadjusted linear mixedeffects analyses of change from baseline in ullanlinna narcolepsy scale uns scores, high baseline uns, but not ivig treatment, was associated with a reduction in narcolepsy symptoms. To validate the chinese version of ullanlinna narcolepsy scale cuns. In a consecutive series of 18 subjects with narcolepsy and definite cataplexy, patients with undetectable. The sample was composed of nine children 5 boys with a mean age of 14. Eleven questionnaire items assessing the main manifestations of narcolepsy formed a measure called the ullanlinna narcolepsy scale uns, which has been validated.
Dec 15, 2014 this page lists resources of potential interest for people seeking to learn more about narcolepsy. But how well does it compare with other narcolepsy scales. We used an international crosssectional questionnaire survey of children aged from 4 to 18 years who. We also show that if ullanlinna narcolepsy scale score is less than 9, narcolepsy is highly unlikely. Aug 27, 2018 the epworth sleepiness scale ess, the ullanlinna narcolepsy scale uns, and more recently the swiss narcolepsy scale sns were used as screening tools for narcolepsy. Microsoft word epworth sleepiness scale narcolepsy scale. We ascertained patients with physiciandiagnosed narcolepsy in king county, washington using multiple overlapping methods over four years starting july 2001. Additional narcolepsy symptomsadditional narcolepsy symptoms please take a minute to answer the following questions to determine if you may suffer from narcolepsy. A validity study of ullanlinna narcolepsy scale in hong kong.
A total score above 14 is suggestive of narcolepsy with cataplexy. Created to assess individuals who may have narcolepsy with cataplexy. Also, among patients with high baseline uns scores, control patients achieved a uns score ullanlinna narcolepsy scale. Subjects then suspected of having narcolepsy participated in a laboratory investigation, which included polysomnography and hla typing, or were interviewed in detail by telephone. By using the screening questionnaire ullanlinna narcolepsy scale uns at the initial stage and then followed by the phone interviews, polysomnography and hla typing of selected subjects. Narcolepsy is a chronic neurological sleep disorder, the diagnosis of which is based upon clinical evaluation and additional paraclinical assessments. Often less than once a month times a month 12 times a week q2. What is the abbreviation for ullanlinna narcolepsy scale. Sleepewake disturbances 3 years after traumatic brain injury. I sometimes experience muscle weakness or a loss of muscle strength when i laugh or get angry yes no. There was a statistically significant negative correlation between serum iron levels and adhd symptom severity. I sometimes experience muscle weakness or a loss of muscle strength when i laugh or get angry yes no a. Uns abbreviation stands for ullanlinna narcolepsy scale. Sleep science narcolepsy and the sickness impact profile.
Harvard medical schools division of sleep medicine and its sleep and health education program assume no responsibility for content on external sites, nor does listing here indicate any editorial endorsement or approval of the content of these sites. Trained professionals administered inperson interviews to patients using a standardized questionnaire that included demographic information, the epworth sleepiness scale ess, and the ullanlinna narcolepsy scale uns. Journal of sexual medicine 2009, epub ahead of print. Ullanlinna narcolepsy scale uns at the initial stage and then followed by the phone interviews, polysomnography and hla typing of selected subjects. Intravenous immunoglobulin therapy in pediatric narcolepsy. We report an unusually prolonged cataplectic attack in a patient with narcolepsy who stopped fluoxetine to perform sleep investigations. However, as suggested by the authors, this simple but very useful questionnaire needed to be replicated and validated in other ethnic populations,14. Unusually prolonged rebound cataplexy after withdrawal of.
These materials are intended for us residents 18 years of age or older and are not intended to replace a conversation with a sleep specialist. Also, among patients with high baseline uns scores, control patients achieved a uns score narcolepsy. No correlation was found measuring serum ferritin levels. Mar 15, 2017 mean standard deviation followup length was 2. Comparison groups were included to ensure that the scale could accurately distinguish between symptoms of narcolepsy and those of other sleep or fatiguerelated issues e. Sep 01, 2006 narcolepsy hypersomnias narcolepsy hypersomnias 20060901 00. Using the ullanlinna narcolepsy scale uns, we identified three possible narcolepsy patients within the adhd group and no suspects in the control group. Hypocretin orexin deficiency predicts severe objective. Swiss narcolepsy scale sns kit order form thank you for your interest in the swiss narcolepsy scale sns the sns is designed to screen for narcolepsy with cataplexy in patients with excessive daytime sleepiness. To validate ullanlinna narcolepsy scale uns as a screening tool for narcolepsy in a clinical population and to compare it with swiss narcolepsy scale sns and epworth sleepiness scale ess.
A validity study of ullanlinna narcolepsy scale in hong. Uns questionnaires of 267 participants visiting helsinki sleep clinic were analyzed. The psychosocial problems of children with narcolepsy and those. Request pdf ullanlinna narcolepsy scale in diagnosis of narcolepsy study objectives to validate ullanlinna narcolepsy scale uns as a screening tool for narcolepsy in a clinical population. The ullanlinna narcolepsy scale uns was developed by hublin et al.
554 383 668 1283 1216 873 1247 477 126 55 904 1406 1179 1324 1240 1383 952 133 1135 479 567 148 1483 381